| Data | In casa | Ospite | Risultato |
|---|---|---|---|
| 21/01/25 16.30 | Galatasaray Istanbul | Dynamo Kiev | 3:3 |
| 22/01/25 16.30 | Besiktas Istanbul | Athletic Bilbao | -:- |
| 23/01/25 18.45 | AZ Alkmaar | Roma | -:- |
| 23/01/25 18.45 | Malmö FF | FC Twente Enschede | -:- |
| 23/01/25 18.45 | FK Bodö/Glimt | Maccabi Tel Aviv | -:- |
| 23/01/25 18.45 | Qarabag | FCSB Bukarest | -:- |
| 23/01/25 18.45 | Viktoria Pilsen | RSC Anderlecht | -:- |
| 23/01/25 18.45 | 1899 Hoffenheim | Tottenham Hotspur | -:- |
| 23/01/25 18.45 | FC Porto | Olympiacos Pireo | -:- |
| 23/01/25 18.45 | Fenerbahce Istanbul | Olympique Lione | -:- |
| 23/01/25 21.00 | Rigas Futbola Skola | Ajax Amsterdam | -:- |
| 23/01/25 21.00 | PFC Ludogorets Razgrad | FC Midtjylland | -:- |
| 23/01/25 21.00 | Royale Union Saint-Gilloise | Sporting Braga | -:- |
| 23/01/25 21.00 | IF Elfsborg Boras | OGC Nizza | -:- |
| 23/01/25 21.00 | Eintracht Francoforte | Ferencvaros Budapest | -:- |
| 23/01/25 21.00 | Manchester United | Glasgow Rangers | -:- |
| 23/01/25 21.00 | Lazio | Real Sociedad | -:- |
| 23/01/25 21.00 | PAOK Salonicco | Slavia Praga | -:- |