| Data | In casa | Ospite | Risultato |
|---|---|---|---|
| 29/03/25 19.30 | New England Revolution | New York Red Bulls | 2:1 |
| 29/03/25 19.30 | Toronto FC | Vancouver Whitecaps | 0:0 |
| 29/03/25 21.30 | Colorado Rapids | Charlotte FC | 2:0 |
| 30/03/25 00.30 | Atlanta United FC | New York City FC | 4:3 |
| 30/03/25 00.30 | D.C. United | Columbus Crew | 1:2 |
| 30/03/25 00.30 | Inter Miami CF | Philadelphia Union | 2:1 |
| 30/03/25 01.30 | FC Dallas | Sporting Kansas City | 2:1 |
| 30/03/25 01.30 | Chicago Fire | CF Montreal | 1:1 |
| 30/03/25 01.30 | Minnesota United FC | Real Salt Lake | 2:0 |
| 30/03/25 01.30 | Nashville SC | Cincinnati FC | 1:2 |
| 30/03/25 04.30 | San Jose Earthquakes | Seattle Sounders | 1:1 |
| 30/03/25 04.30 | Los Angeles Galaxy | Orlando City | 1:2 |
| 30/03/25 04.30 | San Diego FC | Los Angeles FC | 3:2 |
| 30/03/25 20.15 | St. Louis City SC | Austin FC | 0:1 |
| 31/03/25 01.00 | Portland Timbers | Houston Dynamo | 3:1 |