| Data | In casa | Ospite | Risultato |
|---|---|---|---|
| 21/05/22 16.00 | FK Krasnodar | Achmat Grosny | 1:1 |
| 21/05/22 16.00 | CSKA Mosca | FK Rostov | 4:0 |
| 21/05/22 16.00 | Dynamo Mosca | PFC Sochi | 1:5 |
| 21/05/22 16.00 | FK Nischni Nowgorod | Zenit San Pietroburgo | 1:0 |
| 21/05/22 16.00 | FC Krylia Sovetov Samara | Lokomotive Mosca | 0:1 |
| 21/05/22 16.00 | Rubin Kasan | FK Ufa | 1:2 |
| 21/05/22 16.00 | Arsenal Tula | Ural Jekaterinburg | 1:2 |
| 21/05/22 16.00 | FK Chimki | Spartak Mosca | 2:1 |