| Data | In casa | Ospite | Risultato |
|---|---|---|---|
| 15/05/21 17.00 | Caykur Rizespor | Istanbul Basaksehir FK | 0:2 |
| 15/05/21 17.00 | Fatih Karagümrük | Denizlispor | 5:1 |
| 15/05/21 17.00 | Antalyaspor | Konyaspor | 0:0 |
| 15/05/21 17.00 | Sivasspor | Kasimpasa Istanbul | 2:1 |
| 15/05/21 17.00 | MKE Ankaragücü | Alanyaspor | 0:1 |
| 15/05/21 17.00 | Hatayspor | Gazisehir Gaziantep FK | 0:1 |
| 15/05/21 19.30 | Trabzonspor | Genclerbirligi Ankara | 2:1 |
| 15/05/21 19.30 | Kayserispor | Fenerbahce Istanbul | 1:2 |
| 15/05/21 19.30 | Göztepe Izmir | Besiktas Istanbul | 1:2 |
| 15/05/21 19.30 | Galatasaray Istanbul | Yeni Malatyaspor | 3:1 |