| Data | In casa | Ospite | Risultato |
|---|---|---|---|
| 17/03/19 18.00 | KV Kortrijk | Royal Antwerp FC | 2:0 |
| 17/03/19 18.00 | SV Zulte-Waregem | KRC Genk | 3:3 |
| 17/03/19 18.00 | Standard Liegi | Waasland-Beveren | 4:3 |
| 17/03/19 18.00 | KV Oostende | RSC Anderlecht | 0:2 |
| 17/03/19 18.00 | Sporting Charleroi | KAS Eupen | 1:2 |
| 17/03/19 18.00 | Sint-Truidense VV | KAA Gent | 0:2 |
| 17/03/19 18.00 | Club Brügge | Royal Excel Mouscron | 1:2 |
| 17/03/19 18.00 | KSC Lokeren OV | KSV Cercle Brügge | 3:1 |