| Data | In casa | Ospite | Risultato |
|---|---|---|---|
| 06/05/18 14.30 | Roda JC Kerkrade | ADO Den Haag | 2:3 |
| 06/05/18 14.30 | SC Heerenveen | Feyenoord Rotterdam | 2:3 |
| 06/05/18 14.30 | Sparta Rotterdam | Heracles Almelo | 2:5 |
| 06/05/18 14.30 | PSV Eindhoven | FC Groningen | 0:0 |
| 06/05/18 14.30 | FC Twente Enschede | NAC Breda | 1:1 |
| 06/05/18 14.30 | FC Utrecht | VVV Venlo | 1:0 |
| 06/05/18 14.30 | Willem II Tilburg | Vitesse Arnheim | 2:2 |
| 06/05/18 14.30 | Excelsior Rotterdam | Ajax Amsterdam | 1:2 |
| 06/05/18 14.30 | AZ Alkmaar | PEC Zwolle | 6:0 |